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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '29921647e7e6289800b84d5bde9319d45d9b2400496c507fcf035c9e005d9e4c' 
  AND token = 'j4oQojElNJXCif6Mm2ETicfp77spn5QXW5dVHyha5p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}