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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b80c8d5ce39eaf99e1c82183fbe76499c94d2712a7ba888e56c98658906d9495' 
  AND token = '/jyMOXlt+EBZ9l9xH4nH43a5+ALn0GKDQy4oFKMD6kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}