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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9421790b1884556c4189ad97051c79f50bdda2a9d47047be8d84f10cb5c2be72' 
  AND token = 'ERTe7h/JV/fxoN3/mtB4hZCqvMvr1L5RI3No9tsjT/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}