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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'de861aab2bd51c292b7530d825c029da9fd8895a2389e401ca3d34d031237558' 
  AND token = 'JlrUZR8SBwlrPTkHE/4aokJ9pUaKQJEp0OZo716WhFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}