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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '38355b48ce431e32c6aaf3896e58b88d8978ec18d71a5b9fb73c00258c6f047c' 
  AND token = 'U4tpwcAgdsvG9F/Ldb5VgNapV6ZmzI8Ge7b2dZwa5vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}