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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ef2ead48542669033b91581b90ac5a79b2bd79348c74b58d52dc848237e0e5c' 
  AND token = 'FDeygexNMy1bb5xpS4Syd70nzk04QTS4E7IvuMzjYWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}