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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '529a3121608dff393ca004ad222eb943bf7a8502ebd0bda116ce83f5b9b3be7e' 
  AND token = 'oAO06VpuaX6Ox137wk7ARqizu14YCvRHLi3XSRSVS/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}