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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43faea711a07f9f7d2bec14138ca7be726e68ae21f7bdd0bd1bf4e7454379dfa' 
  AND token = 'OShjilPoa1XhH2YIAgRM0b/aMqYY41ajDKokgTCH6JQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}