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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '486a2da5346ef5ec83dc62b2b2646e784e3d5b0ba76b4806c4ad66bfc6648bcd' 
  AND token = 'bxTfOLQyQiSOFYoC7c+OLhpKcwQLi/ZeEssvSyuVhX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}