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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3b051dd7be1e022bd3d7a17ebe97cfc5367c1f7890c8efdd59c4d5a595f56c05' 
  AND token = 'z1NcBkWktYyXQc3MMGiEMi1XM3afpDDEryThkla2GFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}