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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ac8867468b712261256585e9e2e6986f1a00503c85c5ce7678b8607c31f63897' 
  AND token = 'SN12UK1EmS8iooYUN2ra0DFQwUjyrkD8PszMrnXy/Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}