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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '376219162514b2ba472fee5e41ea474f637c8a0a578f28da5b7a3ca9b6030ab6' 
  AND token = 'CwtA4ym077nQSxxTcy/Z7xJfJGq3tdGygEaGX86KTpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}