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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b1967fea5508bd239e146feee8fc2a7f222e7e6f066da61fcf2fbb1c218405ad' 
  AND token = 'IzED5TufWf+ipzQKOTX/HCXvUqSqnKQLP2QCyfrGzJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}