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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21c39802f0670ed912bae2fac4b2ac0ec0535395c708f02d55c8849d1747ad55' 
  AND token = 'ynzatSlavrtBjSGPysT9KUxKbhVnmry665aEGdgmTFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}