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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a33b1ce171bab66db2e9a8172e5f3ddecf90cf6594017092d0181d431fefbe08' 
  AND token = 'vYmWZyfIYJweuYez7pS2PEg1+mSc8wvbMvAc9hM1QkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}