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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '01b7da07988f9d3c489e24a3c1f1900e2dbfd5155bc0b2421f6f1c69669441fe' 
  AND token = 'fVUf2ENQgS/e41RXVqo1/RhF6iFUM+kWMxud+AdvUbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}