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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9d17366be769cda399c8814a303e6c173d37b36829398d06385d3146a0a967d4' 
  AND token = '2dSKCP3rD4ySSq9SbtJdJq+DtCNxDxeR48jZOqx4rfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}