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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd127b4bf7965131b68077efd2e3ff6768080f726616a3f46b1682f0c67d4bfe4' 
  AND token = 'p6iD1PrI8CWeQsf78ROFkr+gQkBd14obAesDQp36gF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}