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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53899c2247afbc6e75c8b94c9f50ff335242dff9b4c6218aa817366d0a6f15e1' 
  AND token = '+OnmqOR0/2UmICrbiH5FkFaXpubceIH0eXL1GWA8I4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}