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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f90afaeec1f5c7bc9d2702a927698c93a99ecb420dadbddf02918c00d431fa2' 
  AND token = 'FJgf/sA1d77dZVL1tv30H6dUiy/AtRRG2RlIEhfsYrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}