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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8f76c20cc981a44cf9861fbab0fd448232b62efdd9a69087eb796bbed74e169b' 
  AND token = 'Ku1zWrHFhl042zMq9VwtL8NwcMtt+6F4Inur4Y21Tck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}