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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '256ee212632fd63ca82b93cdbcd9fd4b250ead029a0934c331f19ef02e85edb3' 
  AND token = 'iWRNgkrTTwnbk31jwfQ7DAWv+BHSTmB4XHrtQ6EGOkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}