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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd9396f11a5eb591c88181a2780e3643d95e40dca59620eebc2490754298ad9b5' 
  AND token = 'D968e5wzll0YEptOMg7fx+pcXsywafdmneOh5jc3kJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}