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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e059b10c9e7327691180c287c65495fe58473265433403d1584ce134d14495b6' 
  AND token = 'oIy7RBLF9l3JyNBpxy4bx2g+ntf728zjXvrhbEB6IkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}