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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'bfaf5c50773cdbde3f531471dfe96864174796054ea1832ec4c40a3eab5bd849' 
  AND token = 'PGiaZgFA6PKP8LG0q06Qc5uyPUVuWjIINZ0RKVpVrOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}