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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '001309eefbe44c564c6be84b55cb426ead806bcff5c0051b6267859a6a5c52c4' 
  AND token = 'wHGPkUvCAjZkgL9IkarIeIvLfCPHBp486QzzcgSoQmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}