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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b22016d97170786c8ad7beb4cdd9e0706e13fa0e4e4028e034184e088eee1ee6' 
  AND token = 'ZxSNZ/5RGbiVtJYVvvtTRGWY1G4DEA1oZWI0HTlQBkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}