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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2a1c1f7a88e200d98a80df4f1c54307ac91c14248e081145737d113740564b52' 
  AND token = 'm7T/GDmvrwiaa9mnnw/VbvuUq8reIDx7MebAxDZOwAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}