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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9ba325f059d8a0558355a357f468db8644aa7de7feb820e76f44871c01275bb4' 
  AND token = 'OPuR0v3NoL2lEJJlWCGerNmiVLSCHB6CRjy5yXvqSIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}