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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e7e00e1c437d895e9cada34fb2c5650be0f424ed8a93506d8f3efe9cd1cc001a' 
  AND token = 'ZCguDTTz34S8kbr3QpGOXA0cI4xdBy77wKs+yMeREeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}