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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5e78f6bd7bc71e4b16bd5ea3efd853316b9741d56a86d9f338029121da013fdd' 
  AND token = 'aDsyo1pBUo974dxNDVBnL691nRUJnNYnOCN6KJY0fmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}