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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '643ef3d31796378c2ab85db0b5e8fd2471aec78df87717b0cab0867fe9a2e9ea' 
  AND token = 'bR0dH+M0xN7hrvzqUCc7uTymRbO+RmuEPTw1gTlur68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}