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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c330eced237a8a4b2fa3a18503fb2c6aeac59b289cf34e813c4a7d21e5e05401' 
  AND token = 'UhAWY9y1X4r/ZPNDnk7drgm6xsVGHYcT1bpOZj/QAH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}