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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c00856e0bb1856badbcee81a159aeef937ce447988c64eaabacb9bb2a19ea355' 
  AND token = 'CN+ElqPSNHbUijBX7arZhWGiQsFc/LROtzDtm83mvlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}