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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1278579af203d7d7fd1b5d36c29c19abd3ec35e24792ebae3768711aeeb5a9c1' 
  AND token = 'WKZtFZvz3yZBk06rkByDjJKCl7G5DEcZ/8RCOi1Tl9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}