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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c80b32988b11dbe12b65014dcd80393cd4307ffb8b5c9f79a6fc25c8ab72e59' 
  AND token = 'vw3CGQI/gxIPPL6s6foM+px+iY20emE2m9rAwx8Q2E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}