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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f8a40db4d49a1f863b2d461005a5b83bc2aab39220992a6a06540f972f5bf043' 
  AND token = 'l/6xSm3bwx/YWmvamplC1nGmab4wEgzpESPgMUA6zUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}