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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e7a3e4f6a09f8ec354f82ce52bd38769ebd629a9e0154cea8671b7aa0aa4d95c' 
  AND token = '2vSdTMd99+PNZ/U827qfVVPQCjffOaZDo/ygJN3Xjs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}