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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49723d1f7e8443a8f70f375a7e7ee7e527dc582333f4e28f7f019f801f06121d' 
  AND token = 'djxi6M45aopnQlf4WvtVYyt8CRG3UpwK799H8xV/Nts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}