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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21dcd99d296be5ad28962cfb3be9e1fbb1f8fd977f74823bb9e21b6481eb641e' 
  AND token = 'tnShDalezpcpDEb9TFmm5tLH6KK8TSkqaN+dhhOW6Go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}