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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46c3f050001563cd157550f8dbd382f17319b3e0495ab570e79f9f3454099b42' 
  AND token = 'btTqpY4CBxefSiAXfPTSDgIi9A12LdAMRvp8Q6e09K8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}