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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f8c06c10f330c0e400575201f9c12d07416e8dc30562509272099057718a0347' 
  AND token = 'Umh7tAj29FwBNPHb1SnQOr92Bf9kzEW9ffX7ZIfk8HU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}