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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '59f58a9da14afd602983888cca622c28c27fa7e6f758bbccc5585875ccfcb682' 
  AND token = 'xZyc/W0OPXSkOCDQW/I+EeEMsBKXeGnBcL6ASX3awKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}