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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e7d523074acbcb18e228de56c6af2c7bb853aca96f52025efc01da9f9f0914df' 
  AND token = 'bVxU/+msSNvuvyYaWQeP2MHdeZNE8CxvPGeOShS80xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}