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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '779e003deea0048558f67c2c974a18af655dc9ae545c9b6f25d7f604e08a05dd' 
  AND token = '8L7qtFdoev8qKF8wPDjvulFPIhhNaehl80Dn1thOPFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}