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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'eda3252a5e8bddb6f318b191e8e3cc73295cf935e24cfde34b828f9feac25d24' 
  AND token = 'O7kjO9S48ue0/7rDx2iCK4PnZ6WGE54b6o45IJKp7cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}