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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9278badb756bca4e623a044aaf2fd91401fee328e9f2367d752431634869ecae' 
  AND token = 'NiikxIxGalCUWft+0R+NEel+Jw/BCeHL8xit7BGXupU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}