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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b647a11f3056ee274ac3fdfe0ec6ef89dcfa656125f801a9daa77f961a64c405' 
  AND token = 'O1e+wfMi9eSTe/pbvkJcDN156NXBDDknFJ9ykuu/mQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}