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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e46b27bb1266808a1dddfe4a814dc9aca10814762c7108fd049d10c5d77a5721' 
  AND token = 'NNLbsqrpRmx7wsUiJx0H3C6T5OCVSYxmbJeCBmAdnn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}