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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0c22273610c4f570eaf9795f3bb19583bef2eb854f185505492523edf07af9d0' 
  AND token = 'ixOJ42XAuT8uInQkQQerwjGfaqvND/uVTo7u+LNCkt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}